A6553
DL-2-Amino-5-phosphonovaleric acid lithium salt
~95%
Synonym(s):
DL-2-Amino-5-phosphonopentanoic acid, AP-5
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
C5H11NO5PLi
CAS Number:
Molecular Weight:
203.06
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.26
Recommended Products
Assay
~95%
Quality Level
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
SMILES string
[Li].NC(CCCP(O)(O)=O)C(O)=O
InChI
1S/C5H12NO5P.Li.H/c6-4(5(7)8)2-1-3-12(9,10)11;;/h4H,1-3,6H2,(H,7,8)(H2,9,10,11);;
InChI key
QIVHTKSFMZBERS-UHFFFAOYSA-N
Gene Information
rat ... Grik1(29559) , Grin2a(24409) , Grin2b(24410)
Related Categories
Biochem/physiol Actions
DL-2-Amino-5-phosphonovaleric acid is a selective N-methyl-d-aspartate (NMDA) receptor antagonist used frequently in studies of neurological processes
Anticonvulsant; potent and selective antagonist for NMDA receptors.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Thomas K Fung et al.
Synapse (New York, N.Y.), 65(7), 677-686 (2010-12-31)
Synaptic plasticity may depend not only on the afferent fibers but also on the recipient structure. The medial perforant path (MPP) from the entorhinalcortex projects to both the dentate gyrus (DG) and CA3, resulting in excitatory postsynaptic potentials (EPSPs) in
Guan Cao et al.
Journal of neurophysiology, 107(3), 902-912 (2011-11-25)
Long-term potentiation (LTP) is a form of synaptic plasticity thought to underlie memory; thus knowing its developmental profile is fundamental to understanding function. Like memory, LTP has multiple phases with distinct timing and mechanisms. The late phase of LTP (L-LTP)
A Osorio-Espinoza et al.
Neuroscience, 176, 20-31 (2011-01-05)
The globus pallidus, a neuronal nucleus involved in the control of motor behavior, expresses high levels of histamine H(3) receptors (H(3)Rs) most likely located on the synaptic afferents to the nucleus. In this work we studied the effect of the
Jessica M André et al.
Neuropharmacology, 60(4), 617-625 (2010-12-21)
NMDA glutamate receptors (NMDARs) and nicotinic acetylcholine receptors (nAChRs) are both involved in learning and synaptic plasticity. Increasing evidence suggests processes mediated by these receptors may interact to modulate learning; however, little is known about the neural substrates involved in
Brandon S Martin et al.
Journal of neurophysiology, 112(4), 890-902 (2014-05-23)
Fragile X syndrome (FXS) is the leading cause of inherited intellectual disability. Comorbidities of FXS such as autism are increasingly linked to imbalances in excitation and inhibition (E/I) as well as dysfunction in GABAergic transmission in a number of brain
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service