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90278

Sigma-Aldrich

Triethanolamine

BioUltra, ≥99.5% (GC)

Synonym(s):

2,2′,2′′-Nitrilotriethanol, Tris(2-hydroxyethyl)amine

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About This Item

Linear Formula:
(HOCH2CH2)3N
CAS Number:
102-71-6
Molecular Weight:
149.19
Beilstein:
1699263
EC Number:
203-049-8
MDL number:
MFCD00002855
UNSPSC Code:
12161700
PubChem Substance ID:
57653379
NACRES:
NA.25

vapor density

5.14 (vs air)

Quality Level

200

vapor pressure

0.01 mmHg ( 20 °C)

product line

BioUltra

Assay

≥99.5% (GC)

form

liquid
viscous liquid

autoignition temp.

600 °F

expl. lim.

8.5 %

impurities

insoluble matter, passes filter test
≤0.1% ethanolamine (GC)
≤0.2% water
≤0.3% diethanolamine (GC)

ign. residue

≤0.1% (as SO4)

refractive index

n20/D 1.485 (lit.)
n20/D 1.485

pH

10.5-11.5 (25 °C, 1 M in H2O)

useful pH range

7.3-8.3

pKa (25 °C)

7.8

bp

190-193 °C/5 mmHg (lit.)

mp

17.9-21 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

density

1.124 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤1 mg/kg
sulfate (SO42-): ≤20 mg/kg

cation traces

Al: ≤2 mg/kg
As: ≤0.1 mg/kg
Ba: ≤1 mg/kg
Bi: ≤2 mg/kg
Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Li: ≤1 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Mo: ≤1 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

SMILES string

OCCN(CCO)CCO

absorption

cut-off at 270 nm in H2O at 1 M

λ

1 M in H2O

UV absorption

λ: 280 nm Amax: 0.1

InChI

1S/C6H15NO3/c8-4-1-7(2-5-9)3-6-10/h8-10H,1-6H2

InChI key

GSEJCLTVZPLZKY-UHFFFAOYSA-N

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Application

Triethanolamine (TEA), an emulsifier, surfactant and capping agent, may be used to study its toxicity profile and mechanisms. TEA may be used in various drug delivery constructs to improve drug solubility. TEA may be used to cap CdTe nanoparticles.

Other Notes

Buffer in recommended method for alanine amionopeptidase in urine

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

354.2 °F - closed cup

Flash Point(C)

179 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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H Mattenheimer et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 26(10), 635-644 (1988-10-01)
A method is recommended for the measurement of the catalytic concentration of alanine aminopeptidase in the urine of man, rat, and dog, using L-alanine-4-nitroanilide as substrate. In currently used methods, substrate concentrations between 1.7 and 2.0 mmol/l are used. Kinetic
Xiaoxuan Liu et al.
Molecular pharmaceutics, 9(3), 470-481 (2012-01-03)
Successful achievement of RNA interference in therapeutic applications requires safe and efficient vectors for siRNA delivery. In the present study, we demonstrate that a triethanolamine (TEA)-core PAMAM dendrimer of generation 5 (G(5)) is able to deliver sticky siRNAs bearing complementary
Kostas Karatasos et al.
Macromolecular bioscience, 12(2), 225-240 (2011-12-08)
In this work we report, compare and discuss the results obtained from fully atomistic molecular dynamics simulations of generations 4, 5, and 6 of PAMAM-based dendrimers having NH(3) and triethanolamine as cores, forming complexes with a short interfering RNA (siRNA)
Stuart K Langley et al.
Dalton transactions (Cambridge, England : 2003), 41(32), 9789-9796 (2012-07-11)
The synthesis, structures and magnetic properties of two new mixed-valence heptanuclear manganese clusters are described. Both complexes utilize triethanolamine (teaH(3)) as a bridging ligand, displaying near planar, disc-like metal topologies and are of formulae [Mn(II)(4)Mn(IV)(3)(tea)(teaH(2))(3)(peolH)(4)](BF(4))(2)·solv (1) and [Mn(II)(4)Mn(III)(3)F(3)(tea)(teaH)(teaH(2))(2)(piv)(4)(Hpiv)(chp)(3)]·0.5MeCN (2). Compound
Liviu Ungur et al.
Journal of the American Chemical Society, 134(45), 18554-18557 (2012-11-01)
A toroidal magnetic moment in the absence of conventional total magnetic moment is observed in a {Dy(6)} ring. The reason for the net toroidal arrangement of the local magnetic moments is the high symmetry of the complex in combination with
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