53340

L-Histidine dihydrochloride

≥99.0% (AT)

• Synonym(s): L-Histidine hydrochloride (1:2)
• Empirical Formula (Hill Notation): C₆H₉N₃O₂ · 2HCl
• CAS Number: 6027-02-7
• Molecular Weight: 228.08
• Beilstein: 6119230
• EC Number: 227-890-5
• MDL number: MFCD00066569
• UNSPSC Code: 12352209
• PubChem Substance ID: 57651406
• NACRES: NA.26

Properties

• Quality Level: 100
• Assay: ≥99.0% (AT)
• form: powder or crystals
• optical activity: [α]20/D +6.5±1°, c = 8% in H₂O
• ign. residue: ≤0.1% (as SO₄)
• color: white
• mp: 240-245 °C (dec.)
• solubility: H₂O: soluble; saline: soluble
• anion traces: sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: As: ≤0.1 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; NH₄⁺: ≤500 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• SMILES string: Cl.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2.2ClH/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);2*1H/t5-;;/m0../s1
• InChI key: XEJCDBUNISUVGZ-XRIGFGBMSA-N

Description

Biochem/physiol Actions

L-Histidine is a natural proteinogenic α amino acid useful as a cell growth supplement that support protein and peptide biosynthesis. L-Histidine is studied in a wide range of applications that involve imidazole chemistry and biochemisty.

L-Histidine is a positively charged imidazole-side chain containing α amino acid. It is metabolized to histamine and is a precursor of the dipeptide carnosine. As one of the 22 proteinogenic amino acids L-His is incorporated into proteins by translation processes in vitro. L-Histidine is an essential amino acid added to cell culture media.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves