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53271

Sigma-Aldrich

Mito Red

suitable for fluorescence, ≥70% (HPLC)

Synonym(s):

3,6-Bis(diethylamino)-9-[2-(4-methylcoumarin-7-yloxycarbonyl)phenyl]xanthylium chloride, Rhodamine B 4-methylumbelliferyl ester chloride

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About This Item

Empirical Formula (Hill Notation):
C38H37ClN2O5
CAS Number:
1021902-10-2
Molecular Weight:
637.16
MDL number:
MFCD05664720
UNSPSC Code:
12352200
PubChem Substance ID:
329757927
NACRES:
NA.32

Quality Level

100

Assay

≥70% (HPLC)

form

solid

fluorescence

λex 569 nm; λem 594 nm in DMSO

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

[Cl-].CCN(CC)c1ccc2c(-c3ccccc3C(=O)Oc4ccc5C(C)=CC(=O)Oc5c4)c6ccc(cc6[o+]c2c1)N(CC)CC

InChI

1S/C38H37N2O5.ClH/c1-6-39(7-2)25-14-17-31-33(21-25)44-34-22-26(40(8-3)9-4)15-18-32(34)37(31)29-12-10-11-13-30(29)38(42)43-27-16-19-28-24(5)20-36(41)45-35(28)23-27;/h10-23H,6-9H2,1-5H3;1H/q+1;/p-1

InChI key

XCVSDCPWJRHMSZ-UHFFFAOYSA-M

General description

Mito Red is a cell membrane permeable rhodamine based dye. It localizes mitochondria, and emits red fluorescence. The interaction of Mito Red with mitochondria depends of the membrane potential of the mitochondria. Mitochondria can be stained with 20-200 nM of Mito Red.

Application

MitoRed (Mito Red), a vital dye and mitochondrial stain, is used to indicate the status of mitochondria under various physiological and physical conditions.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Human cell, 21(1), 7-11 (2008-01-15)
We investigated the mitochondrial behavior, localization and heteroplasmy in reconstituted oocytes derived from germinal vesicle (GV) transfers. The karyoplast containing the GV nucleus and the ooplast (enucleated oocyte) were prepared from GV oocytes derived from B6D2F1 mice. Mitochondria in the
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Digestive diseases and sciences, 50 Suppl 1, S76-S83 (2005-09-27)
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