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Phenylephrine hydrochloride for peak identification

Name: Phenylephrine hydrochloride for peak identification
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(R)-(−)-Phenylephrine hydrochloride, (R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride

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About This Item

Linear Formula:

HOC₆H₄CH(CH₂NHCH₃)OH·HCl

CAS Number:

61-76-7

Molecular Weight:

203.67

Beilstein:

4158948

MDL number:

MFCD00012605

UNSPSC Code:

41116107

PubChem Substance ID:

329831094

NACRES:

NA.24

grade

pharmaceutical primary standard

API family

phenylephrine

manufacturer/tradename

EDQM

mp

143-145 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC1=CC([C@H](CNC)O)=CC=C1.Cl

InChI

1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

InChI key

OCYSGIYOVXAGKQ-FVGYRXGTSA-N

Gene Information

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

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Analytical Reference Materials for the Pharma Industry

Pharmacopeia & Metrological Institute Standards

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phenylephrine hydrochloride for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.

Description

Pricing

Signal Word

Warning

Hazard Statements

H302 - H317

Precautionary Statements

P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Lot/Batch Number

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Minimally invasive intraoperative estimation of left-ventricular end-systolic elastance with phenylephrine as loading intervention.

C A Boly et al.

British journal of anaesthesia, 111(5), 750-758 (2013-07-11)

Left-ventricular end-systolic elastance (Ees) is an index of cardiac contractility, but the invasive nature of its assessment has limited perioperative application. We explored the feasibility of a minimally invasive method of Ees estimation for perioperative assessment of cardiac function and

Role of nitric oxide in optic nerve head blood flow regulation during isometric exercise in healthy humans.

Doreen Schmidl et al.

Investigative ophthalmology & visual science, 54(3), 1964-1970 (2013-02-27)

We determined whether administration of a nitric oxide synthase (NOS) inhibitor alters optic nerve head blood flow (ONHBF) regulation during isometric exercise in healthy subjects. Our study was done in a randomized, placebo-controlled, double-masked, three-way crossover design. A total of

Vasoconstrictor responses to vasopressor agents in human pulmonary and radial arteries: an in vitro study.

Dale A Currigan et al.

Anesthesiology, 121(5), 930-936 (2014-09-10)

Vasopressor drugs, commonly used to treat systemic hypotension and maintain organ perfusion, may also induce regional vasoconstriction in specialized vascular beds such as the lung. An increase in pulmonary vascular tone may adversely affect patients with pulmonary hypertension or right

Effect of phenylephrine on the haemodynamic state and cerebral oxygen saturation during anaesthesia in the upright position.

P F Soeding et al.

British journal of anaesthesia, 111(2), 229-234 (2013-03-23)

The upright sitting or beachchair position is associated with hypotension, risk of cerebral hypoperfusion, and cerebral injury. We hypothesized that by increasing arterial pressure with phenylephrine administration, cerebral perfusion, and postoperative recovery would be improved. Thirty-four patients undergoing elective shoulder

Imaging the iris with swept-source optical coherence tomography: relationship between iris volume and primary angle closure.

Heather Mak et al.

Ophthalmology, 120(12), 2517-2524 (2013-07-16)

To measure iris volume and anterior segment parameters using a swept-source anterior segment optical coherence tomography (OCT) and investigate factors associated with iris volume and iris volume change after pupil dilation in eyes with open angles and angle closure. Cross-sectional

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