ABT337

Anti-NANOS1 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Nanos homolog 1, NOS1, NANOS1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: rat, human
• technique(s): immunohistochemistry: suitable; western blot: suitable
• UniProt accession no.: Q8WY41
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... NANOS1(340719)

Description

General description

Nanos homolog 1 (NANOS1, NOS-1) contains one nanos-type zinc finger and belongs to the nanos family. It is an RNA-binding protein that is predominantly expressed in testis during germline development. NANOS 1 is highly expressed in lung carcinomas that can be detected in invasive tumor cells. NANOS1 up-regulates the production of MMP14 to promote tumor cell invasion.

Specificity

This antibody recognizes the intermediate domain of NANOS1.

Immunogen

Epitope: Intermediate domain

KLH-conjugated linear peptide corresponding to the intermediate domain of human NANOS1.

Application

Detect Nanos homolog 1 using this rabbit polyclonal antibody, Anti-NANOS1 Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected NANOS1 in human brain tissue.

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

Quality

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected NANOS1 in 15 µg of rat brain tissue lysate.

Target description

~42 kDa observed

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Rat brain tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable