218746
Caspase-1 Inhibitor VI
Caspase-1 Inhibitor VI, Z-YVAD-FMK, is a potent, cell-permeable, and irreversible inhibitor of caspase-1, caspase-4, and caspase-5.
Synonym(s):
Caspase-1 Inhibitor VI, Z-YVAD-FMK
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About This Item
Empirical Formula (Hill Notation):
C31H39FN4O9
Molecular Weight:
630.66
UNSPSC Code:
12352200
Recommended Products
Quality Level
Assay
≥95% (HPLC)
≥95% (TLC)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
color
white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
A potent, cell-permeable and irreversible inhibitor of caspase-1 (ICE).
A potent, cell-permeable, and irreversible inhibitor of caspase-1 (ICE), caspase-4, and caspase-5.
Biochem/physiol Actions
Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Sequence
Z-Tyr-Val-Ala-Asp(OMe)-CH₂F*
Other Notes
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.
Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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