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biological source
human
Quality Level
form
liquid
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... MRAS(22808)
General description
GST fusion-protein, corresponding to Ras Binding Domain of Raf-1, provided bound to glutathione agarose.
Product Source: Human Ras Binding Domain (RBD, residues 1-149) of Raf-1, expressed in E. coli.
Quality
Routinely evaluated by Affinity Precipitation/Immunoblot Analysis
Storage and Stability
1 year at -20°C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Yves Moulard et al.
Analytica chimica acta, 700(1-2), 126-136 (2011-07-12)
Liquid chromatography-mass spectrometry (LC-MS) has been widely used in doping control laboratories over the last two decades. Currently, simple quadrupole, triple quadrupole and ion trap are the most commonly employed analyzers in toxicological analysis. Nevertheless, the main lack of these
The lutropin/choriogonadotropin receptor-induced phosphorylation of the extracellular signal-regulated kinases in leydig cells is mediated by a protein kinase a-dependent activation of ras
Hirakawa, T. and Ascoli, M.
Molecular Endocrinology, 17, 2189-2200 (2003)
Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition.
Charette, N; De Saeger, C; Lannoy, V; Horsmans, Y; Leclercq, I; Starkel, P
Molecular Cancer null
C K Szekeres et al.
The Journal of biological chemistry, 275(49), 38831-38841 (2000-08-23)
12(S)-Hydroxyeicosatetraenoic acid (12(S)-HETE), a 12-lipoxygenase metabolite of arachidonic acid, has multiple effects on tumor and endothelial cells, including stimulation of invasion and angiogenesis. However, the signaling mechanisms controlling these physiological processes are poorly understood. In a human epidermoid carcinoma cell
The hepatitis B virus HBx protein inhibits caspase 3 activity
Gottlob, K., et al
The Journal of Biological Chemistry, 273, 33347-33353 (1998)
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