Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

870451O

Avanti

2-OG

Avanti Polar Lipids 870451O

Synonym(s):

2-oleoyl glycerol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C21H40O4
CAS Number:
3443-84-3
Molecular Weight:
356.54
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 5 mg (with screw cap/argon/foil bag (870451O-5mg))

manufacturer/tradename

Avanti Polar Lipids 870451O

lipid type

phosphoglycerides
bioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(CO)(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO

InChI

1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-

InChI key

UPWGQKDVAURUGE-KTKRTIGZSA-N

General description

2-oleoyl glycerol (2-OG) is synthesized from trioleoylglycerol from the reaction catalyzed from pancreatic lipase (PL).

Application

2-oleoyl glycerol (2-OG) is suitable for use in a lipidomic study.

Biochem/physiol Actions

2-oleoyl glycerol (2-OG) acts as an agonist for G protein-coupled receptor 119 (GPR119) in vitro and stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo.

Packaging

5 mL PTFE Vial with Screw Cap/Argon/Foil Bag (870451O-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
Hansen KB, et al.
The Journal of Clinical Endocrinology and Metabolism, 96(9), E1409-E1417 (2011)
Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides
Tortoriello G, et al.
PLoS ONE, 8(7), e67865-e67865 (2013)
Ieva Vasiliauskaité-Brooks et al.
Nature, 544(7648), 120-123 (2017-03-23)
Adiponectin receptors (ADIPORs) are integral membrane proteins that control glucose and lipid metabolism by mediating, at least in part, a cellular ceramidase activity that catalyses the hydrolysis of ceramide to produce sphingosine and a free fatty acid (FFA). The crystal

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service