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870314C

Avanti

18:1 DGS

Avanti Research™ - A Croda Brand 870314C

Synonym(s):

1,2-dioleoyl-sn-glycero-3-succinate

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About This Item

Empirical Formula (Hill Notation):
C43H76O8
CAS Number:
127640-49-7
Molecular Weight:
721.06
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (870314C-25mg)
pkg of 2 × 4 mL (870314C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870314C

concentration

10 mg/mL (870314C-25mg)
25 mg/mL (870314C-200mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COC(CCC(O)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C43H76O8/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(46)49-37-39(38-50-42(47)36-35-40(44)45)51-43(48)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38H2,1-2H3,(H,44,45)/b19-17-,20-18-/t39-/m1/s1

InChI key

VZGIZLLBNVAMQT-NYVOMTAGSA-N

General description

18:1 DGS or 1,2-dioleoyl-sn-glycero-3-succinate (DOSG) is a non-phospholipid. This lipid contains double oleoyl chains and all of this chains form stable fluidic bilayers.

Application

1,2-dioleoyl-sn-glycero-3-succinate (DOSG) or 18:1 DGS has been used in liposome preparation.

Packaging

5 mL Clear Glass Sealed Ampule (870314C-200mg)
5 mL Clear Glass Sealed Ampule (870314C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Delivery of superoxide dismutase to pulmonary epithelium via pH-sensitive liposomes
Briscoe P, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 268(3), L374-L380 (1995)
Lipid-dependent gating of a voltage-gated potassium channel
Zheng H, et al.
Nature Communications, 2(3), 250-250 (2011)
Sungsoo Lee et al.
Journal of visualized experiments : JoVE, (77), e50436-e50436 (2013-07-31)
To study the lipid-protein interaction in a reductionistic fashion, it is necessary to incorporate the membrane proteins into membranes of well-defined lipid composition. We are studying the lipid-dependent gating effects in a prototype voltage-gated potassium (Kv) channel, and have worked

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