810240P

TopFluor^® TMR PA

Avanti Polar Lipids 810240P, powder

• Synonym(s): 1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3- phosphate (ammonium salt)
• Empirical Formula (Hill Notation): C₄₈H₇₄ BF₂N₄ O₁₀P
• CAS Number: 2260795-39-7
• Molecular Weight: 946.90
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 mg (810240P-1mg)
• manufacturer/tradename: Avanti Polar Lipids 810240P
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

Phosphatidic acid (PA) is a diacyl-glycerophospholipid that consists of a glycerol and an alcohol moiety, having two fatty acids and a phosphate group esterified at positions 1, 2, and 3, respectively.

Biochem/physiol Actions

Phosphatidic acid (PA) is a signaling molecule that is synthesized in the endoplasmic reticulum (ER). It is transported to the mitochondrial outer membrane to stimulate mitofusin (Mfn)-mediated fusion. PA is a major intermediate metabolite involved in the synthesis of membrane glycerophospholipids, which include phosphatidylcholine (PC), phosphatidylserine (PS), phosphatidylethanolamine (PE), and phosphatidylserine (PS).

Packaging

5 mL Amber Glass Screw Cap Vial (810240P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

TopFluor is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3