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O3132

Sigma-Aldrich

Oxibendazole

~98%

Synonym(s):

Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O3
CAS Number:
20559-55-1
Molecular Weight:
249.27
EC Number:
243-877-7
MDL number:
MFCD00133728
UNSPSC Code:
12352100
PubChem Substance ID:
57654481
NACRES:
NA.22

Assay

~98%

Quality Level

100

storage temp.

2-8°C

SMILES string

CCCOc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

RAOCRURYZCVHMG-UHFFFAOYSA-N

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Biochem/physiol Actions

Anthelminthic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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G W Lubega et al.
Biochemical pharmacology, 41(1), 93-101 (1991-01-01)
The low- and high-affinity binding of tritiated benzimidazole anthelmintics (mebendazole and oxibendazole) to tubulin-containing supernatants derived from unembryonated eggs, third stage larvae or adult worms of thiabendazole-susceptible and -resistant strains of Haemonchus contortus were examined and compared. The displacement of
R P Herd et al.
Veterinary parasitology, 48(1-4), 229-240 (1993-06-01)
Environmental consequences of treating horses with recommended dosages of ivermectin paste were studied in two controlled experiments with 29 horses in Ohio. In 1988, dung dispersal rates were measured by changes in dry weight over time of 48 copromes (300
C Gokbulut et al.
Research in veterinary science, 72(1), 11-15 (2002-05-11)
Oxibendazole (OBZ) was administered to eight horses at an oral dose of 10 mg kg(-1) bodyweight each. Parent OBZ could only be detected in plasma at the 0.5 and 1.0 hours post administration sampling times and the mean maximum plasma
C R Reinemeyer et al.
Journal of the American Veterinary Medical Association, 206(11), 1710-1715 (1995-06-01)
Forty 11- to 12-week-old helminth-naive Beagles were categorized by sex and weight and randomly assigned to 4 treatment groups (group 1, ivermectin/pyrantel pamoate; group 2, milbemycin oxime; group 3, untreated control; group 4, diethylcarbamazine/oxibendazole). Each pup was inoculated PO with
Ray M Kaplan et al.
Journal of the American Veterinary Medical Association, 225(6), 903-910 (2004-10-16)
To determine prevalence of anthelmintic resistance in cyathostome nematodes of horses in the southern United States. Cross-sectional study. 786 horses on 44 farms and stables in Georgia, South Carolina, Florida, Kentucky, and Louisiana. Fecal egg count (FEC) reduction tests were
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