512338

4-(Hydroxymethyl)phenylboronic acid

≥95%

• Synonym(s): α-Hydroxy-p-tolueneboronic acid, 4-Hydroxymethylbenzeneboronic acid
• Linear Formula: HOCH₂C₆H₄B(OH)₂
• CAS Number: 59016-93-2
• Molecular Weight: 151.96
• MDL number: MFCD00792672
• UNSPSC Code: 12352103
• PubChem Substance ID: 24873622
• NACRES: NA.22

Properties

• Assay: ≥95%
• mp: 251-256 °C (lit.)
• functional group: hydroxyl
• SMILES string: OCc1ccc(cc1)B(O)O
• InChI: 1S/C7H9BO3/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4,9-11H,5H2
• InChI key: PZRPBPMLSSNFOM-UHFFFAOYSA-N

Description

Application

Reactant involved in the synthesis of biologically active compounds including:

• Imidazo[4,5-b]pyrazin-2-ones for use as mTOR kinase inhibitors
• Human immunodificiency virus protease inhibitors with activity against resistant viruses

Reactant involved in:

• Suzuki coupling reactions
• Copper-catalyzed transformation from arylboronic acids in water

Involved in the synthesis of polyurethane containing spindle-type chromophores

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves