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434248

Sigma-Aldrich

L-Abrine

99%

Synonym(s):

Nα-Methyl-L-tryptophan

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About This Item

Empirical Formula (Hill Notation):
C12H14N2O2
CAS Number:
526-31-8
Molecular Weight:
218.25
Beilstein:
86638
EC Number:
208-388-5
MDL number:
MFCD00005645
UNSPSC Code:
12352200
PubChem Substance ID:
24867181
NACRES:
NA.22

Quality Level

100

Assay

99%

optical activity

[α]20/D +65°, c = 1 in 0.5 M NaOH

reaction suitability

reaction type: solution phase peptide synthesis

mp

>300 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CN[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI

1S/C12H14N2O2/c1-13-11(12(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,13-14H,6H2,1H3,(H,15,16)/t11-/m0/s1

InChI key

CZCIKBSVHDNIDH-NSHDSACASA-N

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Biochem/physiol Actions

An indoleamino acid that shows radical scavenging and antioxidant properties in vitro.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Maximilian Huber et al.
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Emilie Gauthy et al.
PloS one, 8(9), e76186-e76186 (2013-10-08)
GARP is a transmembrane protein present on stimulated human regulatory T lymphocytes (Tregs), but not on other T lymphocytes (Th cells). It presents the latent form of TGF-β1 on the Treg surface. We report here that GARP favors the cleavage
Huixi Zou et al.
Journal of natural products, 72(1), 44-52 (2008-12-31)
This study reports that a series of tryptophan derivatives with modifications on the side chain or at the indole ring were accepted by two cyclic dipeptide prenyltransferases, CdpNPT and FtmPT1, and converted to prenylated derivatives. The structures of the enzymatic

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