Skip to Content
Merck
All Photos(2)

Key Documents

More Documents

130850

Sigma-Aldrich

3-Butyn-1-ol

97%

Synonym(s):

3-Butynol

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
HC≡CCH2CH2OH
CAS Number:
927-74-2
Molecular Weight:
70.09
Beilstein:
773710
EC Number:
213-161-9
MDL number:
MFCD00002955
UNSPSC Code:
12352100
eCl@ss:
39020335
PubChem Substance ID:
24847980
NACRES:
NA.22

Assay

97%

form

liquid

refractive index

n20/D 1.441 (lit.)

bp

128.9 °C (lit.)

mp

−63.6 °C (lit.)

density

0.926 g/mL at 25 °C (lit.)

SMILES string

OCCC#C

InChI

1S/C4H6O/c1-2-3-4-5/h1,5H,3-4H2

InChI key

OTJZCIYGRUNXTP-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

The enthalpies of combustion and vaporization of 3-butyn-1-ol is measured by static bomb combustion calorimetry and correlation gas chromatography techniques.

Application

3-Butyn-1-ol was used to prepare Markovnikov addition product.
Alkynyl substrate used in a study of a palladium-catalyzed coupling with β-tetrionic acid bromide leading to alkynyl substituted furanones in good yield.
Synthon for preparation of oxygen-containing heterocycles and protected esters of s-Hydroxy-L-isoleucine

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

96.8 °F - closed cup

Flash Point(C)

36 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Deniz Dogruer et al.
Bioorganic & medicinal chemistry letters, 14(2), 523-526 (2003-12-31)
The binding of a series pyridylbutynylamines 6 was examined at alpha4beta2 nACh receptors. Structural modifications, comparing 6 with pyridyl ethers 2, did not consistently result in parallel effects on receptor affinity, suggesting possible differences in their modes of binding. Furthermore
Sumod A Pullarkat et al.
Inorganic chemistry, 45(18), 7455-7463 (2006-08-29)
Alcohol functionalized diphosphine ligands with chirality residing on the carbon backbone were prepared using a novel two-stage asymmetric synthetic methodology from the corresponding terminal alkynols. Under mild conditions, the alkynols, 3-butyn-1-ol and 2-propyn-1-ol, were subjected to direct hydrophosphination to give
Tetrahedron Letters, 48, 105-105 (2007)
Kopf, Henning; Pietraszuk. et al.
Organometallics, 25(10), 2533-2546 (2006)
Johanna E Grimm et al.
Journal of agricultural and food chemistry, 67(20), 5838-5846 (2019-05-06)
An aroma extract dilution analysis applied to the volatiles isolated from jackfruit ( Artocarpus heterophyllus Lam.) pulp by solvent extraction and solvent-assisted flavor evaporation resulted in the detection of 48 odorants with flavor dilution (FD) factors between 1 and ≥8192.
View All Related Papers

Articles

Functionalized Alkynes

Alkynes contain a highly versatile functional group that may be utilized for numerous reactions such as electrophilic additions of hydrogen, halogens, hydrogen halides, or water; metathesis; hydroboration; oxidative cleavage; C–C coupling; and cycloadditions

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service