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PHL89794

Sinomenine hydrochloride

phyproof® Reference Substance

Synonym(s):

(9a,13a,14a)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-one hydrochloride, Cucoline hydrochloride, Kukolin hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C19H23NO4 · HCl
CAS Number:
6080-33-7
Molecular Weight:
365.85
MDL number:
MFCD01714307
UNSPSC Code:
41116107

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥98.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

SMILES string

OC1=C(OC)C=CC(C2)=C1[C@]3(CC(C(OC)=C4)=O)[C@@]4([H])[C@H]2N(C)CC3.Cl

InChI

1S/C19H23NO4.ClH/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19;/h4-5,9,12-13,22H,6-8,10H2,1-3H3;1H/t12-,13+,19-;/m1./s1

InChI key

YMEVIMJAUHZFMW-VUIDNZEBSA-N

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General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Sinomenine is a herbal medicine used to treat inflammatory diseases like rheumatoid arthritis. Sinomenine had anti-inflammatory effects in several animal models of inflammation, and inhibits mast cell degranulation and histamine release. Additionally, Sinomenine potentiates renewal of human embryonic stem cells.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
70171279

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