SML1786

Centhaquin

≥98% (HPLC)

• Synonym(s): 2-[2-[4-(3-Methylphenyl)-1-piperazinyl]ethyl]quinoline, Centhaquine
• Empirical Formula (Hill Notation): C₂₂H₂₅N₃
• CAS Number: 57961-90-7
• Molecular Weight: 331.45
• MDL number: MFCD01685420
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: CC1=CC=CC(N(CC2)CCN2CCC3=NC4=CC=CC=C4C=C3)=C1
• InChI: 1S/C22H25N3/c1-18-5-4-7-21(17-18)25-15-13-24(14-16-25)12-11-20-10-9-19-6-2-3-8-22(19)23-20/h2-10,17H,11-16H2,1H3
• InChI key: UJNWGFBJUHIJKK-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Centhaquin is a centrally acting hypotensive agent. Centhaquin is an effective resuscitative agent that improves cardiac output, reduces blood lactate levels, and improves survival time of hemorrhaged rats. Centhaquin exhibits antinociception in the mouse mediated through the opioid, the α2A and α2B adrenoceptors.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H413
• Precautionary Statements: P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable