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Key Documents

SML0651

Sigma-Aldrich

OAC1

≥98% (HPLC)

Synonym(s):

N-1H-Pyrrolo[2,3-c]pyridin-5-yl-benzamide

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About This Item

Empirical Formula (Hill Notation):
C14H11N3O
CAS Number:
Molecular Weight:
237.26
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)

InChI key

HWJRIFZDXJKJJN-UHFFFAOYSA-N

Biochem/physiol Actions

OAC1 enhances iPSC reprogramming efficiency by enhancing Oct4 and Nanog driven gene expression. Treatment of mouse embryonic fibroblasts transduced with Oct2, Sox2, Klf4 and c-myc displayed a two-fold increase in the formation of ESC-like clones. OAC1 treated cells display a hypomethylated state of Oct4 promoter DNA.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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