SBR00020

Zearalenone Ready Made Solution

1 mg/mL in DMSO

• Synonym(s): (3S,11E)-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-,1H-2-benzoxacyclotetradecin-1,7(8H)-dione, F-2 toxin
• Empirical Formula (Hill Notation): C₁₈H₂₂O₅
• CAS Number: 17924-92-4
• Molecular Weight: 318.36
• MDL number: MFCD00133085
• UNSPSC Code: 85151701
• NACRES: NA.28

Properties

• form: liquid
• concentration: 1 mg/mL in DMSO
• storage temp.: −20°C
• SMILES string: O1[C@H](CCCC(=O)CCC\C=C\c2c(c(cc(c2)O)O)C1=O)C
• InChI: 1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1
• InChI key: MBMQEIFVQACCCH-QBODLPLBSA-N

Description

Biochem/physiol Actions

Zearalenone, a fungal mycotoxin produced by Fusarium graminearum, binds estrogen receptor (ER) causing conformational alteration to the receptor. Zearalenone is a common contaminant in cereal grain used for animal and human food. It exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans. Furthermore, zearalenone was found to act as an immune-toxic compound, which can cause food consumption reduction in rats.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): 188.6 °F - closed cup
• Flash Point(C): 87 °C - closed cup