N5536

Nefazodone hydrochloride

≥98% (HPLC), solid, antidepressant

• Synonym(s): 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride, BMY-13754, MJ-13754-1, Serzone
• Empirical Formula (Hill Notation): C₂₅H₃₂ClN₅O₂ · HCl
• CAS Number: 82752-99-6
• Molecular Weight: 506.47
• MDL number: MFCD00935760
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724551
• NACRES: NA.77

Properties

• product name: Nefazodone hydrochloride, ≥98% (HPLC), solid
• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: white
• solubility: DMSO: ≥10 mg/mL; H₂O: insoluble
• originator: Bristol-Myers Squibb
• SMILES string: O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.Cl
• InChI: 1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H
• InChI key: DYCKFEBIOUQECE-UHFFFAOYSA-N
• Gene Information: human ... HTR2A(3356) , HTR2C(3358) , SLC6A2(6530) , SLC6A4(6532)

Description

Biochem/physiol Actions

Novel antidepressant; mixed 5-HT_2A serotonin receptor antagonist/serotonin uptake inhibitor.

Features and Benefits

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves