G1146

L-Glutamine–Penicillin–Streptomycin solution

with 200 mM L-glutamine, 10,000 U penicillin and 10 mg steptomycin/mL in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for cell culture

• Synonym(s): Pen/Strep, Penicillin/Streptomycin
• MDL number: MFCD00283636
• UNSPSC Code: 12352207
• NACRES: NA.76

Properties

• biological source: synthetic
• Quality Level: 300
• sterility: 0.1 μm filtered
• product line: BioReagent
• form: liquid
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• Mode of action: cell wall synthesis | interferes; protein synthesis | interferes
• shipped in: dry ice
• storage temp.: −20°C

Description

Application

Used to reduce or eliminate bacterial contamination in cell, especially primary cell, cultures. Recommended for use in cell culture applications at 10 ml/L.

Biochem/physiol Actions

Mode of Action: Glutamine is essential as an energy source for most mammalian cells in culture because of its amino acid carbon skeleton. Penicillin acts by inhibiting bacterial cell wall synthesis. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome and causes miscoding.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.

Components

Formulated with 200 mM L-glutamine, 10,000 units/ml penicillin, and 10 mg/ml streptomycin in 0.9% sodium chloride.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H317 - H334
• Precautionary Statements: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable