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50637

Sigma-Aldrich

Decanoyl-L-carnitine

≥94.0% (HPLC)

Synonym(s):

(2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxodecyl)oxy]-1-propanaminium inner salt, L-Carnitine decanoyl ester, C10-Carnitine

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About This Item

Empirical Formula (Hill Notation):
C17H33NO4
CAS Number:
3992-45-8
Molecular Weight:
315.45
Beilstein:
4145305
UNSPSC Code:
12352211
PubChem Substance ID:
329757616
NACRES:
NA.26

Quality Level

100

Assay

≥94.0% (HPLC)

form

powder or crystals

optical activity

[α]/D -15±3°, c = 1 in H2O

impurities

≤10% water

functional group

ester

storage temp.

2-8°C

SMILES string

C[N+](C)(C)C[C@H](OC(CCCCCCCCC)=O)CC([O-])=O

InChI

1S/C17H33NO4/c1-5-6-7-8-9-10-11-12-17(21)22-15(13-16(19)20)14-18(2,3)4/h15H,5-14H2,1-4H3/t15-/m1/s1

InChI key

LZOSYCMHQXPBFU-OAHLLOKOSA-N

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Biochem/physiol Actions

Decanoylcarnitine is useful in the diagnosis of fatty acid oxidation disorders and differentiation between biochemical phenotypes of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency deficiencyoxidation disorders.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sarah K Davies et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(29), 10761-10766 (2014-07-09)
Sleep restriction and circadian clock disruption are associated with metabolic disorders such as obesity, insulin resistance, and diabetes. The metabolic pathways involved in human sleep, however, have yet to be investigated with the use of a metabolomics approach. Here we
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Journal of separation science, 39(2), 247-255 (2015-11-01)
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Fotouh R Mansour et al.
Biomedical chromatography : BMC, 27(10), 1339-1353 (2013-09-06)
Carnitine and its acylesters are a family of compounds that can be used in the early diagnosis of many diseases. Carnitine and acylcarnitines have a crucial role in fatty acid transportation. The increased level of free carnitine, total carnitine, or
Christoph Nowak et al.
Scientific reports, 8(1), 8691-8691 (2018-06-08)
Insulin resistance (IR) predisposes to type 2 diabetes and cardiovascular disease but its causes are incompletely understood. Metabolic challenges like the oral glucose tolerance test (OGTT) can reveal pathogenic mechanisms. We aimed to discover associations of IR with metabolite trajectories
Wajih Anwer et al.
Biophysical journal, 118(5), 1032-1043 (2020-02-07)
Excessive accumulation of acylcarnitines (ACs), often caused by metabolic disorders, has been associated with obesity, arrhythmias, cardiac ischemia, insulin resistance, etc. Mechanisms whereby elevated ACs might contribute to pathophysiological effects remain largely unexplored. We have aimed to gain insight into
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