472301
Dimethyl sulfoxide
ACS reagent, ≥99.9%
Synonym(s):
DMSO
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About This Item
Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
Beilstein:
506008
EC Number:
MDL number:
UNSPSC Code:
12191502
PubChem Substance ID:
NACRES:
NA.21
grade:
ACS reagent
Assay:
≥99.9%
bp:
189 °C (lit.)
vapor pressure:
0.42 mmHg ( 20 °C)
Recommended Products
grade
ACS reagent
Quality Level
vapor density
2.7 (vs air)
vapor pressure
0.42 mmHg ( 20 °C)
Assay
≥99.9%
form
liquid
autoignition temp.
573 °F
expl. lim.
42 %, 63 °F
impurities
≤0.001 meq/g Titr. acid
≤0.1% water
evapn. residue
≤0.01%
color
clear colorless
refractive index
n20/D 1.479 (lit.)
bp
189 °C (lit.)
mp
16-19 °C (lit.)
density
1.10 g/mL (lit.)
SMILES string
CS(C)=O
InChI
1S/C2H6OS/c1-4(2)3/h1-2H3
InChI key
IAZDPXIOMUYVGZ-UHFFFAOYSA-N
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General description
Dimethyl sulfoxide is an organosulfur, commonly used as a polar solvent that can dissolve a wide range of polar and non-polar compounds. It is also utilized as a reaction reagent in several well-known processes, including swern oxidation, 2a pfitzner-moffatt oxidation, 2b, and the corey-chaykovsky reaction.
Application
Dimethyl sulfoxide (DMSO) has been used:
- in the preparation of ethyl 4-[18F]fluorobenzoate.
- in the culture medium for 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay.
- as a solvent in chemical synthesis.
- to dissolve and prepare stock solutions of small molecules, drugs, and chemical compounds for various assays and experiments.
Caution
Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.
Other Notes
For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table
Dimethyl Sulfoxide Miscibility/Immiscibility Table
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
188.6 °F - closed cup
Flash Point(C)
87 °C - closed cup
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