SYNPLE-H011

Reagent-cartridge Morpholine-2-spiro-(4-Pip)

Synple

• Synonym(s): Synple 2
• MDL number: MFCD32903606
• UNSPSC Code: 12161503
• NACRES: NA.22

Properties

• Quality Level: 100
• parameter: up to 0.5 mmol scale

Description

General description

Reagent-cartridge Morpholine-2-spiro-(4-Pip) is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the synthesis of a morpholine-piperidine spirocycle from an aldehyde through the use of a SnAP reagent. The cartridge contains all necessary reagents for transforming the chosen aldehyde into a morpholine-piperidine spirocycle.

Scale: up to 0.5 mmol
Heterocycle: Morpholine-piperdine spirocycle
Compatible substrates: aldehyde

Cartridge contents:

• Immobilized SnAP reagent
• Cu catalyst (Cu(OTF)₂ and 2,6-lutidinium triflate)
• SCX (for purification)
• Silica (for purification)

Related Cartridges:

• SYNPLE-H001Reagent-cartridge Morpholine
• SYNPLE-H002Reagent-cartridge Oxazepane
• SYNPLE-H004Reagent-cartridge 2-Methylmorpholine
• SYNPLE-H005Reagent-cartridge Piperazine
• SYNPLE-H006Reagent-cartridge Diazepane
• SYNPLE-H007Reagent-cartridge 3-Methylmorpholine
• SYNPLE-H010Reagent-cartridge Morpholine-2-spiro-(2-Pyr)
• SYNPLE-H090Reagent-cartridge 9-OMe-Benzoxazepane
• SYNPLE-H091Reagent-cartridge 7-Br-9-OMe-Benzoxazepane

Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform

• Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
• Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety - all chemicals are contained in the system, minimizing the user′s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system - simple installation
• Reaction temperatures from 25 °C - 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol

Other Notes

An integrated console for capsule-based, automated organic synthesis

For more information on heterocycle formation using SnAP reagents, visit here: SnAP Technology Spotlight

Legal Information

Product of Synple Chem AG

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H411
• Precautionary Statements: P264 - P270 - P273 - P301 + P312 - P391 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable