90964

Hydrogen chloride solution

3 M in methanol, for GC derivatization, LiChropur^™

• Synonym(s): Methanolic HCl
• Empirical Formula (Hill Notation): HCl
• CAS Number: 7647-01-0
• Molecular Weight: 36.46
• MDL number: MFCD00011324
• UNSPSC Code: 12352301
• NACRES: NA.05

Properties

• grade: for GC derivatization
• Quality Level: 100
• form: liquid
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Acylations
• concentration: 3 M in methanol
• technique(s): gas chromatography (GC): suitable
• density: 0.871-0.881 g/mL at 20 °C
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: Cl
• InChI: 1S/ClH/h1H
• InChI key: VEXZGXHMUGYJMC-UHFFFAOYSA-N

Description

General description

Methanolic HCl (hydrogen chloride in methanol) is particularly useful for preparing methyl esters of volatile (short chain) fatty acids. Fatty acids are esterified by heating them with an anhydrous alcohol (e.g., methanol) in the presence of an acidic catalyst (e.g., HCl) in a sealed vessel at a high temperature for a short time. In the reaction, a fatty acid molecule and an alcohol molecule are joined, with the release of a water molecule. The derivatives can be quickly and easily recovered, quantitatively, from the reaction medium.

Application

Learn more in the Product Information

Suitable for derivatization of corticosteroids, estrogens, fatty acids, hop and beer bitter acids, lipids and formic and acetic acid (in cigarette smoke).

Features and Benefits

• Derivatization of fatty acids, particularly volatile (short chain) fatty acids
• Clean reaction (no side reaction) with volatile by-products
• Provides clean, fast, quantitative derivatization

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS05,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H290 - H301 + H311 + H331 - H315 - H319 - H335 - H370
• Precautionary Statements: P210 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup