09-1810
Diethyl ether
≥99.0%, SAJ first grade
Synonym(s):
Et2O, Ethoxyethane, Ether, Ethyl ether
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About This Item
Linear Formula:
(CH3CH2)2O
CAS Number:
Molecular Weight:
74.12
Beilstein:
1696894
MDL number:
UNSPSC Code:
12352112
PubChem Substance ID:
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product name
Diethyl ether, SAJ first grade, ≥99.0%
grade
SAJ first grade
vapor density
2.6 (vs air)
vapor pressure
28.5 psi
Assay
≥99.0%
form
liquid
autoignition temp.
320 °F
expl. lim.
36.5 %
availability
available only in Japan
refractive index
n20/D 1.3530 (lit.)
bp
34.6 °C (lit.)
mp
−116 °C (lit.)
density
0.706 g/mL at 25 °C (lit.)
SMILES string
CCOCC
InChI
1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3
InChI key
RTZKZFJDLAIYFH-UHFFFAOYSA-N
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Application
- Determination of chloropropanol esters and glycidyl esters in nutritional foods by gas chromatography-tandem mass spectrometry based on acid hydrolysis and solid-phase extraction.: This study utilizes diethyl ether in the solid-phase extraction process to determine harmful esters in food products, showcasing its role in enhancing the efficiency of contaminant isolation and detection in complex matrices (Li Y et al., 2024).
- Cloning, Expression, Characterization and Immobilization of a Recombinant Carboxylesterase from the Halophilic Archaeon, Halobacterium salinarum NCR-1.: Research employs diethyl ether for the extraction and purification steps in enzyme characterization, underlining its critical utility in biotechnological applications for enzyme stability and activity studies (Ortega-de la Rosa ND et al., 2024).
- The Analysis of Leontopodium leontopodioides (Willd.) Beauv. Chemical Composition by GC/MS and UPLC-Q-Orbitrap MS.: Diethyl ether is used as an extraction solvent to analyze the chemical composition of medicinal plants, highlighting its effectiveness in capturing a broad spectrum of volatile and semi-volatile compounds (Chen Y et al., 2024).
- Chemical composition and antimicrobial study of Crossobamon orientalis body oil.: In this research, diethyl ether is used for the extraction of essential oils, demonstrating its efficacy in obtaining bioactive compounds for antimicrobial studies (Ahmad S et al., 2024).
- A Static Headspace Gas Chromatography Method for Quantitation of Residual Solvents in Nanoformulations.: Utilizes diethyl ether in a novel static headspace analysis technique for the quantification of residual solvents, showing its applicability in ensuring safety and compliance in pharmaceutical formulations (Kattel K et al., 2024).
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Flam. Liq. 1 - STOT SE 3
Target Organs
Respiratory system
Supplementary Hazards
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
-49.0 °F
Flash Point(C)
-45 °C
Certificates of Analysis (COA)
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Juan E Camacho Londoño et al.
European heart journal, 36(33), 2257-2266 (2015-06-13)
Pathological cardiac hypertrophy is a major predictor for the development of cardiac diseases. It is associated with chronic neurohumoral stimulation and with altered cardiac Ca(2+) signalling in cardiomyocytes. TRPC proteins form agonist-induced cation channels, but their functional role for Ca(2+)
Faysal Benaskar et al.
ChemSusChem, 6(2), 353-366 (2012-11-30)
A μ(2)-process in the Ullmann-type C-O coupling of potassium phenolate and 4-chloropyridine was successfully performed in a combined microwave (MW) and microflow process. Selective MW absorption in a micro-fixed-bed reactor (μ-FBR) by using a supported Cu nanocatalyst resulted in an
Ether-directed ortho-C-H olefination with a palladium(II)/monoprotected amino acid catalyst.
Gang Li et al.
Angewandte Chemie (International ed. in English), 52(4), 1245-1247 (2012-12-15)
Tatsuya Yoshino et al.
Organic letters, 14(16), 4290-4292 (2012-08-09)
A highly efficient total synthesis of the 11-membered cyclic aspercyclides A (1) and B (2) has been achieved by chemo- and regioselective intramolecular oxidative C-O bond formation from differently substituted diphenols.
Alessandra Forni et al.
Journal of molecular graphics & modelling, 38, 31-39 (2012-10-23)
The solvent effect on the I⋯O halogen bonding in complexes of iodobenzene derivatives with formaldehyde has been investigated by systematically varying the substituents on the iodobenzene ring. Calculations have been performed at MP2 and DFT levels of theory, using the
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