PCC300C15C

Pellicon^® Capsule with Ultracel^® Membrane

C Screen, 1.5 m² AseptiQuik^® G connectors

• Synonym(s): Pellicon^® Capsule with Ultracel^® Membrane
• UNSPSC Code: 23151806

Properties

• material: EPDM rubber seal; PPO/PS blend (core); PPO/PS blend housing; TPE seal; composite regenerated cellulose (CRC) membrane; epoxy adhesive; polyester screen; polypropylene screen; polyurethane adhesive
• Quality Level: 400
• sterility: sterile; γ-irradiated
• product line: Pellicon^®
• feature: holdup volume 456 mL (in feed channel); holdup volume 741 mL (in permeate channel)
• packaging: package of 1
• parameter: max. inlet pressure at 75 psi (5.1 bar) and 4-30 °C; max. transmembrane pressure at 45 psi (3.1 bar) and 4-30 °C; 4-6 L/min-m² flow rate
• technique(s): ultrafiltration: suitable
• diam.: 10.3 cm (4.1 in.)
• filtration area: 1.5 m²
• screen size: , Type C screen (coarse screen)
• size: 43.7 cm (17.2 in.) , Length
• impurities: ≤5 ppm Meets TOC (in retentate effluent, after a WFI flush of 20 L/m²)
• matrix: Ultracel^®
• pore size: 300 kDa
• pH range: 2-13
• fitting: inlet/outlet connection for Feed: AseptiQuik^® G Connector; inlet/outlet connection for Permeate: AseptiQuik^® G Connector; inlet/outlet connection for Retentate: AseptiQuik^® G Connector; Permeate: AseptiQuik^® G Connector
• storage temp.: 15-25°C

Description

General description

The Pellicon^® Capsule is the first of its kind -- a true single-use TFF device that comes ready to process in minutes. Self-contained, it employs an easy-to-use, holderless format and is supplied sterilized by irradiation.

Application

Viral Gene Therapies, Vaccines, Concentration, Diafiltration, Buffer exchange, Protein purification, mRNA

Features and Benefits

• Plug ′n play, holderless design - easy to install, safe to remove
• Gamma Sterilized and preseravtive-free - ready to process in minutes
• True single-use, self-contained capusle - fast, safe, and flexible batch turnaround
• Proven Ultracel^® membrane and C screen - high recovery, superior mass transfer, solvent resistance
• Pellicon^® TFF proven performance - true linear scalability within Pellicon^® TFF families

Packaging

A foam clamshell is inserted over the end caps on both ends of the capsule which is then double-bagged and vacuum sealed. The double-bagged capsule is placed on a tray and then individually boxed.

Other Notes

The Emprove^® Program complements the product portfolio through

• Comprehensive documentation to support qualification, risk assessment and process optimization needs.
• Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
• Convenient 24/7 access to up-to-date product information.

Legal Information

AseptiQuik is a registered trademark of Colder Products Company

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany