MAB570
Anti-Heparin Antibody, clone A7.10
clone A7.10, Chemicon®, from mouse
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
A7.10, monoclonal
species reactivity
mouse
should not react with
pig
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
radioimmunoassay: suitable
isotype
IgG2b
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Hdgf(15191)
Specificity
Reacts with mouse heparin. Cross reacts with dextran sulfate by EIA. Also shows some cross reactivity to DNA and heparan sulfate.
Application
Detect Heparin using this Anti-Heparin Antibody, clone A7.10 validated for use in ELISA, RIA.
EIA/RIA (kd by liquid phase RIA for heparin is approximately
1.0 x 10-11 M.) Suggested concentration 1-10 μg/mL.
Inhibits the formation of heparin accelerated thrombin-antithrombin complex formation in vitro.
Optimal working dilutions must be determined by end user.
1.0 x 10-11 M.) Suggested concentration 1-10 μg/mL.
Inhibits the formation of heparin accelerated thrombin-antithrombin complex formation in vitro.
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
ECM Proteins
Physical form
Format: Purified
Purified immunoglobulin. Liquid in 0.02M PB + 0.25M NaCl, pH 7.6 with 0.1% Sodium azide.
Storage and Stability
Maintain at 2-8°C.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Autoimmune MRL mice express high-affinity IgG2b monoclonal autoantibodies to heparin.
Fillit, H, et al.
Clinical Immunology and Immunopathology, 81, 62-67 (1996)
J Qiu et al.
Virology, 269(1), 137-147 (2000-03-22)
Recently heparan sulfate was proposed as the host cell receptor for the dependovirus, adeno-associated virus type 2 (AAV2). We show that although heparan sulfate on the cell surface may contribute to the binding of AAV2 to permissive cells, the amount
E Ortega-Barria et al.
The Journal of biological chemistry, 274(3), 1267-1276 (1999-01-09)
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