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AB5066P

Sigma-Aldrich

Anti-Norepinephrine Transporter Antibody

Chemicon®, from rabbit

Synonym(s):

NET

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

NM_001043.2

UniProt accession no.

P23975

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SLC6A2(6530) , SLC6A5(9152)

Specificity

Specific for Norepinephrine Transporter (NET). Norepinephrine Transporter is a 617 amino acid long integral membrane protein belonging to the Sodium:Neurotransmitter Symporter family (Bruss et al. 1995; Melikian et al. 1994; Pacholczyk et al. 1991) The immunogen peptide shows no significant homology with other other known proteins.

Immunogen

A 22 amino acid peptide sequence mapping to the 1st extracellular domain of rat NET.

Application

This Anti-Norepinephrine Transporter Antibody is validated for use in ELISA, WB for the detection of Norepinephrine Transporter.
Western blot: 1-10 μg/mL (Chemiluminescence technique): NET can exist is at least two forms, a highly glycosylated ~80kDa form is the most common in brain, and a lessly glycosylated 54kDa form is also seen in some regions and tissues.



ELISA: 1:10,000-1:100,000 (50-100 ng immunogen peptide/well) Optimal working dilutions must be determined by the end user.

Target description

80 & 54 kDa

Physical form

Affinity Purified immunoglobulin. Liquid in PBS with 0.1% BSA .

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Functional coupling of serotonin and noradrenaline transporters.
Sandra Horschitz, Rene Hummerich, Patrick Schloss
Journal of Neurochemistry null
Functional characterization of the splicing variants of human norepinephrine transporter.
S Kitayama, K Morita, T Dohi
Neuroscience Letters null
Neurotoxic catecholamine metabolite in nociceptors contributes to painful peripheral neuropathy.
Olayinka A Dina, Sachia G Khasar, Nicole Alessandri-Haber, Oliver Bogen, Xiaojie Chen et al.
The European Journal of Neuroscience null
Effects of chronic unpredictable stress on monoamine transporter immunoreactivity and methamphetamine-induced dopamine release in the nucleus accumbens shell.
Jamie Raudensky, Bryan K Yamamoto
Synapse null
Expression and distribution of dopamine transporter in cardiac tissues of the guinea pig.
Alejandro Reynoso Palomar,Berenice Navarrete Larios,Victoria Chagoya De Sanchez et al.
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