8.17076

TWEEN^® 60 (Polysorbate)

EMPROVE^® ESSENTIAL, Ph. Eur., JPE, NF

• Synonym(s): Polyoxyethylene sorbitan monostearate
• CAS Number: 9005-67-8
• MDL number: MFCD01780110
• UNSPSC Code: 12352104
• EC Index Number: 500-020-4

Properties

• Agency: JPE; NF; Ph. Eur.
• Quality Level: 500
• vapor pressure: <10 hPa ( 20 °C)
• product line: EMPROVE^® ESSENTIAL
• form: viscous liquid
• technique(s): API processing | nano-milling: suitable
• pH: 4,0-7.7 (25 °C, 50 g/L in H₂O)
• kinematic viscosity: 170-320 cSt(40 °C)
• transition temp: flash point >149 °C
• density: 1.1 g/cm³ at 20 °C
• application(s): liquid formulation; ophthalmics; pharma/biopharma processes; pharmaceutical; semi-solid formulation; solid formulation; solubility enhancement
• storage temp.: 15-25°C
• InChI: 1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
• InChI key: HMFKFHLTUCJZJO-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polysorbate 60 is used as surfactant in a variety of liquid formulations and acts e.g. as emulsifying, solubilizing and wetting agent.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

TWEEN is a registered trademark of Croda International PLC

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable