All Photos(1)

Key Documents

48-680MAG

MILLIPLEX MAP Multi-Pathway Magnetic Bead 9-Plex - Cell Signaling Multiplex Assay

Name: MILLIPLEX <small>MAP</small> Multi-Pathway Magnetic Bead 9-Plex - Cell Signaling Multiplex Assay
Brand: MM

Synonym(s):

ERK Cell Signaling Assay, Luminex^® Cell Signaling Assay, Millipore Cell Signaling Assay

Sign Into View Organizational & Contract Pricing

All Photos(1)

About This Item

UNSPSC Code:

12161503

eCl@ss:

32161000

NACRES:

NA.47

Recommended Products

Slide 1 of 5

1 of 5

Millipore

40-012

Luminex 200^™ System

CLS352075

Corning^® Falcon^® Centrifuge Tubes

Y0002021

Microcrystalline cellulose

Supelco

PHR1978

Ibuprofen Related Compound J

Supelco

PHR2814

Tibolone

species reactivity

human

Quality Level

200

manufacturer/tradename

Milliplex^®

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex xMAP)

storage temp.

2-8°C

Related Categories

Immunoassay Platform Solutions

MILLIPLEX^® Multiplex for Luminex^® Immunoassays

General description

The Milliplex^® MAP 9-plex Multi-Pathway Signaling Magnetic Bead kit, phosphoprotein, is used to detect changes in phosphorylated ERK/MAP kinase 1/2 (Thr185/Tyr187), Akt (Ser473), STAT3 (Ser727), JNK (Thr183/Tyr185), p70S6K (Thr412), NFkB (Ser536), STAT5A/B (Tyr694/699), CREB (Ser133), and p38 (Thr180/Tyr182) in cell lysates using the Luminex^® xMAP^® technology. The detection assay is a rapid, convenient alternative to Western Blotting and immunoprecipitation procedures. Each kit has sufficient reagents for one 96-well plate assay.

Specificity

Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Application

Analyze a cell signaling panel using this kit. The analytes available for the cell signaling multiplex assay kit are: CREB (pS133), ERK (pT185/pY187), NFκB (pS536), JNK (pT183/pY185), p38 (Thr180/Tyr182), p70S6K (Thr412), STAT3 (pS727), STAT5A/B (pY694/699), Akt (pS473).

Research Category
Cell Signaling

Research Sub Category
Oncology

Storage and Stability

Recommended storage for kit components is 2 - 8°C

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Legal Information

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Pictograms

GHS05,GHS07,GHS09

Signal Word

Danger

Hazard Statements

H302,H315,H318,H410

Precautionary Statements

P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The endocannabinoid anandamide causes endothelium-dependent vasorelaxation in human mesenteric arteries.

Christopher P Stanley et al.

Pharmacological research, 113(Pt A), 356-363 (2016-10-21)

The endocannabinoid anandamide (AEA) causes vasorelaxation in animal studies. Although circulating AEA levels are increased in many pathologies, little is known about its vascular effects in humans. The aim of this work was to characterise the effects of AEA in

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease.

Lee A Denson et al.

Inflammatory bowel diseases, 25(3), 547-560 (2018-08-21)

Granulocyte-macrophage colony-stimulating factor auto-antibodies (GMAbs) suppress neutrophil-extrinsic GM-CSF signaling and increase risk for stricturing behavior in Crohn's disease (CD). We aimed to define clinical, genomic, and functional associations with neutrophil-intrinsic GM-CSF signaling. Missense mutations in CSF2RA, CSF2RB, JAK2, STAT5A, and

Endothelial Cells Tissue-Specific Origins Affects Their Responsiveness to TGF-β2 during Endothelial-to-Mesenchymal Transition.

Fernanda Ursoli Ferreira et al.

International journal of molecular sciences, 20(3) (2019-01-27)

The endothelial-to-mesenchymal transition (EndMT) is a biological process where endothelial cells (ECs) acquire a fibroblastic phenotype after concomitant loss of the apical-basal polarity and intercellular junction proteins. This process is critical to embryonic development and is involved in diseases such

Osteocalcin does not influence acute or chronic inflammation in human vascular cells.

Sophie A Millar et al.

Journal of cellular physiology, 235(4), 3414-3424 (2019-09-25)

Some human observational studies have suggested an anti-inflammatory role of osteocalcin (OCN). An inflammatory protocol using interferon-γ and tumor necrosis factor-α (10 ng/ml) was employed to examine the acute (24 hr) and chronic (144 hr) effects of uncarboxylated OCN (ucOCN) in commercial, primary

Natural Trienoic Acids as Anticancer Agents: First Stereoselective Synthesis, Cell Cycle Analysis, Induction of Apoptosis, Cell Signaling and Mitochondrial Targeting Studies.

Vladimir A D'yakonov et al.

Cancers, 13(8) (2021-05-01)

The first Z-stereoselective method was developed for the synthesis of unsaturated acids containing a 1Z,5Z,9Z-triene moiety in 61-64% yields using the new Ti-catalyzed cross-coupling of oxygen-containing and aliphatic 1,2-dienes as the key synthetic step. It was shown for the first

View All Related Papers