1.37044

Ethanolamine

EMPROVE^® EXPERT, Ph. Eur., BP, NF

• Synonym(s): Ethanolamine, 2-Aminoethanol, Monoethanolamine
• Empirical Formula (Hill Notation): C₂H₇NO
• CAS Number: 141-43-5
• Molecular Weight: 61.08
• MDL number: MFCD00008183
• UNSPSC Code: 12352104
• EC Index Number: 205-483-3

Properties

• Agency: BP; NF; Ph. Eur.
• Quality Level: 500
• vapor pressure: 0.5 hPa ( 20 °C)
• product line: EMPROVE^® EXPERT
• Assay: 98.0-100.5% (acidimetric)
• form: liquid
• autoignition temp.: 410 °C
• expl. lim.: 3.4-27 % (v/v)
• pH: 12.1 (20 °C, 100 g/L in H₂O)
• kinematic viscosity: 20 cSt(23 °C)
• bp: 171 °C/1013 hPa
• mp: 10.5 °C
• transition temp: flash point 92.5 °C
• density: 1.02 g/cm³ at 20 °C
• application(s): liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical
• storage temp.: 15-25°C
• InChI: 1S/C2H7NO/c3-1-2-4/h4H,1-3H2
• InChI key: HZAXFHJVJLSVMW-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Ethanolamine, a primary amine, is typically used as a buffering agent in small molecule liquid formulations. It may also be used in large molecule downstream purification as a chromatography buffer component.
Due to its low microbial and endotoxin limits, Ethanolamine Emprove^® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302 + H312 + H332,H314,H335,H412
• Precautionary Statements: P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 2
• Flash Point(F): 195.8 °F - Pensky-Martens closed cup
• Flash Point(C): 91 °C - Pensky-Martens closed cup