810110P

12-NBD Stearate

Avanti Research^™ - A Croda Brand 810110P, powder

• Synonym(s): 12-N-methyl-(7-nitrobenz-2-oxa-1,3-diazo)aminostearic acid
• Empirical Formula (Hill Notation): C₂₅H₄₀N₄O₅
• CAS Number: 117056-67-4
• Molecular Weight: 476.61
• MDL number: MFCD00467278
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 mg (810110P-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 810110P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [N+](=O)([O-])c1c2n[o]nc2c(cc1)N(C(CCCCCCCCCCC(=O)O)CCCCCC)C
• InChI: 1S/C25H40N4O5/c1-3-4-5-12-15-20(16-13-10-8-6-7-9-11-14-17-23(30)31)28(2)21-18-19-22(29(32)33)25-24(21)26-34-27-25/h18-20H,3-17H2,1-2H3,(H,30,31)
• InChI key: SAAVELCIPHKGJE-UHFFFAOYSA-N

Description

General description

12-NBD Stearate is amphipathic, nonesterifiable fluorescent fatty acid probe and is a long-chain fatty acid (LCFA) derivative.

Application

12-NBD Stearate has been used in the fluorescent labeling of omega-3 fatty acid in biomaterial films and as a ligand for fatty acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay. It may be used a ligand fluorescence displacement assay of fatty-acid binding protein 5 (FABP5).

Biochem/physiol Actions

12-NBD Stearate incorporated in lipid droplets and is used majorly in fluorescence displacement binding studies of fatty-acid binding proteins. The sterol carrier protein-2 (SCP-2) 15-kDa isoform favours NBD Stearate transport. The uptake of NBD Stearate is regulated by fatty acid binding protein (FABP) expression regulates uptake and inhibited by filipin III.

Packaging

5 mL Amber Glass Screw Cap Vial (810110P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids