902039

4-Methoxypicolinimidamide hydrochloride

≥95%

• Synonym(s): Weix 2-pyridylcarboxamidine ligand for nickel catalysis
• Empirical Formula (Hill Notation): C₇H₁₀ClN₃O
• CAS Number: 1179361-66-0
• Molecular Weight: 187.63
• MDL number: MFCD12755550
• UNSPSC Code: 12352101
• NACRES: NA.22

Properties

• Assay: ≥95%
• form: powder or solid
• reaction suitability: core: nickel; reaction type: Cross Couplings; reagent type: catalyst
• mp: 174-176 °C
• InChI: 1S/C7H9N3O.ClH/c1-11-5-2-3-10-6(4-5)7(8)9;/h2-4H,1H3,(H3,8,9);1H
• InChI key: JOUDWIBACXLPIO-UHFFFAOYSA-N

Description

Application

This pyridyl carboxamidine ligand has been demonstrated by Daniel Weix′s lab to enable nickel-catalyzed cross-coupling of diverse basic nitrogen heterocycles with primary and secondary alkyl halides.

Other Notes

Coupling of Challenging Heteroaryl Halides with Alkyl Halides via Nickel-Catalyzed Cross-Electrophile Coupling

New ligands for nickel catalysis from diverse pharmaceutical heterocycle libraries

Electrochemical Nickel Catalysis for Sp²-Sp³ Cross-Electrophile Coupling Reactions of Unactivated Alkyl Halides

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable