712523
O-(3-Carboxypropyl)-O′-[2-(3-mercaptopropionylamino)ethyl]-polyethylene glycol
Mw 5000
Synonym(s):
Polyethylene glycol, α-Mercapto-ω-carboxy-PEG
About This Item
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form
lumps
mol wt
Mw 5000
reaction suitability
reagent type: cross-linking reagent
Ω-end
thiol
α-end
carboxylic acid
storage temp.
−20°C
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Packaging
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
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Articles
Sigma-Aldrich.com presents an article regarding Polyethylene Glycol Building Blocks for PEGylation.
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.
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