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Key Documents

374229

Sigma-Aldrich

Boc-Tyr-OH

98%

Synonym(s):

N-(tert-Butoxycarbonyl)-L-tyrosine, Boc-L-tyrosine

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About This Item

Linear Formula:
4-(HO)C6H4CH2CH(COOH)NHC(O)OC(CH3)3
CAS Number:
Molecular Weight:
281.30
Beilstein:
2816406
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

solid

optical activity

[α]20/D +3.0°, c = 2 in acetic acid

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

133-135 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C14H19NO5/c1-14(2,3)20-13(19)15-11(12(17)18)8-9-4-6-10(16)7-5-9/h4-7,11,16H,8H2,1-3H3,(H,15,19)(H,17,18)/t11-/m0/s1

InChI key

CNBUSIJNWNXLQQ-NSHDSACASA-N

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Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Abe D Pressman et al.
Journal of the American Chemical Society, 141(15), 6213-6223 (2019-03-27)
Molecular evolution can be conceptualized as a walk over a "fitness landscape", or the function of fitness (e.g., catalytic activity) over the space of all possible sequences. Understanding evolution requires knowing the structure of the fitness landscape and identifying the
Yifan Wang et al.
ACS catalysis, 9(6), 4764-4776 (2019-07-30)
LmbB2 is a peroxygenase-like enzyme that hydroxylates L-tyrosine to L-3,4-dihydroxyphenylalanine (DOPA) in the presence of hydrogen peroxide. However, its heme cofactor is ligated by a proximal histidine, not cysteine. We show that LmbB2 can oxidize L-tyrosine analogs with ring-deactivated substituents
Karoly Toth et al.
Antiviral research, 153, 1-9 (2018-03-07)
Human adenoviruses (AdV) cause generally mild infections of the respiratory and GI tracts as well as some other tissues. However, AdV can cause serious infection in severely immunosuppressed individuals, especially pediatric patients undergoing allogeneic hematopoietic stem cell transplantation, where mortality
Qi Zhao et al.
Nutrition & metabolism, 15, 57-57 (2018-08-18)
Individuals' peak bone mineral density (BMD) achieved and maintained at ages 20-40 years is the most powerful predictor of low bone mass and osteoporotic fractures later in life. The aim of this study was to identify metabolomic factors associated with peak
M L Da Silva et al.
Archives of biochemistry and biophysics, 312(1), 151-157 (1994-07-01)
The N-linked oligosaccharides from porcine fibrinogen were purified following their release from glycopeptides using N-glycosidase F. In separate experiments, both sialyl and asialyl oligosaccharides were prepared from 5 g of fibrinogen. The reducing oligosaccharides were reacted with ammonium bicarbonate to

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