262528

N,N-Diisopropylmethylphosphonamidic chloride

95%

• Synonym(s): Chloro(diisopropylamino)methoxyphosphine, Methyl N,N-diisopropylchlorophosphoramidite, Methyl N,N-diisopropylphosphoramidochloridite
• Linear Formula: [(CH₃)₂CH]₂NP(OCH₃)Cl
• CAS Number: 86030-43-5
• Molecular Weight: 197.64
• Beilstein: 3600769
• MDL number: MFCD00009859
• UNSPSC Code: 12352001
• PubChem Substance ID: 24855746
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 95%
• form: liquid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling
• refractive index: n20/D 1.468 (lit.)
• bp: 34-35 °C/0.8 mmHg (lit.)
• density: 1.018 g/mL at 25 °C (lit.)
• SMILES string: COP(Cl)N(C(C)C)C(C)C
• InChI: 1S/C7H17ClNOP/c1-6(2)9(7(3)4)11(8)10-5/h6-7H,1-5H3
• InChI key: VOVWQRQDSCYAEA-UHFFFAOYSA-N

Description

Application

Reagent used for polymer-supported deoxyoligonucleotide and oligoribonucleotide syntheses.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 161.6 °F - closed cup
• Flash Point(C): 72 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves