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Key Documents

130249

Sigma-Aldrich

2-Nitrophenylacetic acid

98%

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About This Item

Linear Formula:
O2NC6H4CH2CO2H
CAS Number:
Molecular Weight:
181.15
Beilstein:
1959243
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

solid

mp

137-140 °C (lit.)

SMILES string

OC(=O)Cc1ccccc1[N+]([O-])=O

InChI

1S/C8H7NO4/c10-8(11)5-6-3-1-2-4-7(6)9(12)13/h1-4H,5H2,(H,10,11)

InChI key

WMUZDBZPDLHUMW-UHFFFAOYSA-N

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Application

2-Nitrophenylacetic acid was used as an internal standard in the determination of the theophylline solubilizer salicylamide-O-acetic acid.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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H U Schulz et al.
Journal of pharmaceutical and biomedical analysis, 3(5), 469-475 (1985-01-01)
A high-performance liquid chromatographic method for the determination of the theophylline solubilizer salicylamide-O-acetic acid has been developed in the range 0.5 to 10 microg/ml for human serum and 5 to 400 microg/ml for urine. Reversed-phase ion-pair chromatography was employed with
M K Danks et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 5(4), 917-924 (1999-04-23)
Several recent studies have examined the possibility of producing tumor-specific cytotoxicity with various enzyme/ prodrug combinations. The enzymes are targeted to tumor cells either with antibodies (ADEPT, antibody directed enzyme prodrug therapy) or with viruses (VDEPT). The goal of the
Leveraging a small-molecule modification to enable the photoactivation of rho GTPases.
Katryn R Harwood et al.
Chembiochem : a European journal of chemical biology, 10(18), 2855-2857 (2009-10-31)
Manuela F Frasco et al.
The FEBS journal, 274(7), 1849-1861 (2007-03-16)
The poorly known mechanism of inhibition of cholinesterases by inorganic mercury (HgCl2) has been studied with a view to using these enzymes as biomarkers or as biological components of biosensors to survey polluted areas. The inhibition of a variety of
Eric Franqueville et al.
Journal of biotechnology, 97(2), 177-182 (2002-06-18)
The hydrolytic activity of a monoclonal catalytic antibody (9A8) (abzyme) with acetylcholinesterase-like activity was investigated in water-in-oil (w/o) microemulsions (reverse micelles) based on sodium bis-2-(ethylhexyl)sulfosuccinate (AOT) in isooctane, using p- and o-nitrophenylacetate (p-and o-NPA) as substrates. The dependence of the

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