104051
Picolinamide
98%
Synonym(s):
2-Pyridinecarboxamide
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About This Item
Empirical Formula (Hill Notation):
C6H6N2O
CAS Number:
Molecular Weight:
122.12
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
mp
110 °C (dec.) (lit.)
functional group
amide
SMILES string
NC(=O)c1ccccn1
InChI
1S/C6H6N2O/c7-6(9)5-3-1-2-4-8-5/h1-4H,(H2,7,9)
InChI key
IBBMAWULFFBRKK-UHFFFAOYSA-N
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Application
Picolinamide was used as template in preparation of molecular imprinting polymer. Picolinamide was used in a study to evaluate kinetics and mechanism of liberation of picolinamide from chromium(III)-picolinamide complexes in HClO4.
Biochem/physiol Actions
Picolinamide is potential inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells. Picolinamide acts as bidentate ligand and forms complexes with lanthanide nitrates, thiocyanates and perchlorates.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets.
H Yamamoto et al.
Biochemical and biophysical research communications, 95(1), 474-481 (1980-07-16)
Lanthanide complexes with picolinamide.
Condorelli G, et al.
J. Inorg. Nucl. Chem., 36(12), 3763-3766 (1974)
Ángel Manu Martínez et al.
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A practical picolinamide-directed C-H functionalization/alkyne annulation of benzylamine derivatives enabling access to the previously elusive 1,4-dihydroisoquinoline skeleton was developed using molecular O
Study properties of molecular imprinting polymer using a computational approach.
Wu L, et al.
Analyst, 128(7), 944-949 (2003)
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Journal of the American Chemical Society, 134(33), 13546-13549 (2012-08-07)
Tris-arenes based on either isophthalic acid or 2,6-dipicolinic acid have been known for more than a decade to bind anions. Recent studies have also demonstrated their ability to transport various ions through membranes. In this report, we demonstrate two important
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