1428008

Methylene blue

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 3,7-bis(Dimethylamino)phenazathionium chloride, Tetramethylthionine chloride
• Empirical Formula (Hill Notation): C₁₆H₁₈ClN₃S · xH₂O
• CAS Number: 122965-43-9
• Molecular Weight: 319.85 (anhydrous basis)
• Colour Index Number: 52015
• Beilstein: 3599847
• EC Number: 200-515-2
• MDL number: MFCD00150006
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• SMILES string: CN(C)C1=CC=C2C(SC(C3=N2)=CC(C=C3)=[N+](C)C)=C1.[H]O[H].[Cl-]
• InChI: 1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1
• InChI key: WQVSELLRAGBDLX-UHFFFAOYSA-M

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

• Methylene blue as a redox indicator: Recent research has highlighted the application of methylene blue as a redox indicator in radiation-assisted assembly of nanomolybdenum-functionalized covalent organic frameworks, offering advancements in the synthesis and application of these materials for enhanced catalytic performance (Zhang et al., 2024).



• Methylene blue for photocatalytic reduction: A novel approach in the synthesis of nickel oxide has been utilized to explore methylene blue′s role in photocatalytic reduction, demonstrating its potential in environmental applications to degrade pollutants efficiently (Baytar, 2024).



• Methylene blue in antimicrobial activities: This dye′s application extends to bioactive contexts, where it has been used to enhance the antimicrobial properties of enzymes immobilized on green synthesized magnetic nanoparticles, providing a multifunctional approach to bioengineering (Fahim et al., 2024).



• Methylene blue in enzymatic dye decolorization: The compound also plays a role in the decolorization of dyes, leveraging its properties in bioremediation studies focused on the bioactive and enzymatic potential of marine fungi, highlighting its utility in marine environmental management (Wong Chin et al., 2024).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable