1075757

Bisoprolol fumarate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Bisoprolol hemifumarate salt, 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemifumarate salt
• Empirical Formula (Hill Notation): C₁₈H₃₁NO₄ · .5C₄H₄O₄
• CAS Number: 104344-23-2
• Molecular Weight: 383.48
• MDL number: MFCD00792743
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749125
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: bisoprolol
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: OC(=O)\C=C\C(O)=O.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc2ccc(COCCOC(C)C)cc2
• InChI: 1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChI key: VMDFASMUILANOL-WXXKFALUSA-N
• Gene Information: human ... ADRB1(153)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

• Chromatographic Techniques for Assessment of Bisoprolol Fumarate and Perindopril Arginine in Solid Formulations under Various Stress Conditions and Application to Six Sigma, Content Uniformity, and Comparative Dissolution Approaches - Presents advanced chromatographic methods to assess Bisoprolol fumarate in pharmaceutical formulations, crucial for ensuring high standards in drug quality and stability (Mahmoud OA et al., 2023).

Biochem/physiol Actions

Cardioselective β₁-adrenoceptor antagonist.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H302,H361fd,H373
• Precautionary Statements: P202 - P260 - P264 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2 - STOT RE 2
• Target Organs: Heart
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable