T8441

L-Threonine

from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

• Synonym(s): (2S,3R)-2-Amino-3-hydroxybutyric acid
• Linear Formula: CH₃CH(OH)CH(NH₂)CO₂H
• CAS Number: 72-19-5
• Molecular Weight: 119.12
• Beilstein: 1721646
• EC Number: 200-774-1
• MDL number: MFCD00064270
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24900531
• NACRES: NA.26

Properties

• biological source: non-animal source
• Quality Level: 300
• Agency: USP/NF; meets EP testing specifications; meets JP testing specifications; meets USP testing specifications
• product line: BioXtra
• Assay: 99.0-101.0%
• form: powder
• quality: meets EP, JP, USP testing specifications
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• mp: 256 °C (dec.) (lit.)
• solubility: H₂O: 1 g/10 mL, clear, colorless
• application(s): pharmaceutical (small molecule)
• SMILES string: C[C@@H](O)[C@H](N)C(O)=O
• InChI: 1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
• InChI key: AYFVYJQAPQTCCC-GBXIJSLDSA-N

Description

General description

L-Threonine is a naturally occurring amino acid belonging to the aspartate family of amino acids.

Application

L-Threonine has been used for the following :

• To study the effect of heat on homoserine kinase activity
• In Plackett–Burman analysis and then to study the effect of selected amino acids on monoclonal antibody production in CHO cells
• As a substrate to determine the L-threonine dehydrogenase activity
• To study the effect of L-Threonine on the growth rate of P. putida, to check for its tolerance towards L-Threonine

Biochem/physiol Actions

L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for O-linked glycosylation, protein phosphorylation and glycine synthesis.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves