SRP0433
PDE5A1 active murine
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)
Synonym(s):
CN5N, phosphodiesterase 5A, cGMP-specific
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
biological source
mouse
recombinant
expressed in baculovirus infected Sf9 cells
Assay
≥70% (SDS-PAGE)
form
aqueous solution
mol wt
124 kDa
packaging
pkg of 5 μg
storage condition
avoid repeated freeze/thaw cycles
concentration
0.34 mg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
mouse ... PDE5A(242202)
General description
Mouse PDE5A (GenBank Accession No. NM_153422) full length with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Hunter C Champion et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(5), 1661-1666 (2005-01-26)
The molecular mechanism for priapism is not well characterized. Although the nitric oxide (NO) pathway is known to mediate penile erection under normal conditions, we hypothesized that the mechanism of priapism rests in aberrant downstream signaling of this pathway based
Anindita Das et al.
The Journal of biological chemistry, 280(13), 12944-12955 (2005-01-26)
We investigated the effect of sildenafil in protection against necrosis or apoptosis in cardiomyocytes. Adult mouse ventricular myocytes were treated with sildenafil (1 or 10 microM) for 1 h before 40 min of simulated ischemia (SI). Necrosis was determined by
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