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Key Documents

SAB4501571

Sigma-Aldrich

Anti-IRS-1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

IRS-1, IRS1, Insulin receptor substrate-1

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

Pricing and availability is not currently available.

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 131 kDa

species reactivity

mouse, human, rat

concentration

~1 mg/mL

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1 of 4

This Item
T5411PHR2027T0100000
technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

form

liquid

form

-

form

-

form

-

format

single component solution

format

single component solution

format

neat

format

neat

Quality Level

300

Quality Level

200

Quality Level

300

Quality Level

-

grade

certified reference material

grade

drug standard

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

General description

Anti-IRS-1 Antibody detects endogenous levels of total IRS-1 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human IRS-1.

Immunogen Range: 279-328

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Huai-Chia Chuang et al.
    Nature communications, 5, 4602-4602 (2014-08-08)
    Proinflammatory cytokines play important roles in insulin resistance. Here we report that mice with a T-cell-specific conditional knockout of HGK (T-HGK cKO) develop systemic inflammation and insulin resistance. This condition is ameliorated by either IL-6 or IL-17 neutralization. HGK directly
    Rahul Agrawal et al.
    Biochimica et biophysica acta, 1842(9), 1313-1323 (2014-05-21)
    The rising prevalence of type-2 diabetes is becoming a pressing issue based on emerging reports that T2DM can also adversely impact mental health. We have utilized the UCD-T2DM rat model in which the onset of T2DM develops spontaneously across time
    Águeda González-Rodríguez et al.
    Disease models & mechanisms, 7(9), 1093-1100 (2014-07-06)
    Oxidative stress contributes to the progression of acute liver failure (ALF). Transcription factor nuclear factor-erythroid 2-related factor (Nrf2) serves as an endogenous regulator by which cells combat oxidative stress. We have investigated liver damage and the balance between death and

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