All Photos(3)
About This Item
Empirical Formula (Hill Notation):
C7H10N2OS
CAS Number:
Molecular Weight:
170.23
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
Recommended Products
biological source
synthetic (organic)
Assay
≥98%
form
powder
solubility
1 M NH4OH: 50 mg/mL, clear to slightly hazy, colorless to light yellow
SMILES string
CCCC1=CNC(=S)NC1=O
InChI
1S/C7H10N2OS/c1-2-3-5-4-8-7(11)9-6(5)10/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI key
RWJRFPUNLXBCML-UHFFFAOYSA-N
Application
5-Propyl-2-thiouracil (PTU) is used to induce and study mechanisms of hypothyroidism at the levels of thyroid hormone biosynthesis and gene regulation.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Marion F Haug et al.
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Visual acuity, the ability of the visual system to distinguish two separate objects at a given angular distance, is influenced by the optical and neuronal properties of the visual system. Although many factors may contribute, the ultimate limit is photoreceptor
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Endocrinology, 160(8), 1771-1785 (2019-05-29)
The CLARITY-BPA experiment, a large collaboration between the National Institute of Environmental Health Sciences, the National Toxicology Program, and the US Food and Drug Administration, is designed to test the effects of bisphenol A (BPA) on a variety of endocrine
Alessandra Gentili et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 33(12), 1793-1802 (2016-10-04)
This paper describes a rapid method for confirming residues of thyreostats in meat-based baby foods by using liquid chromatography - dual polarity electrospray - tandem mass spectrometry (LC-ES(±)-MS/MS). Six thioureylenes, belonging to the group of thiouracil and imidazole, were selected
Alexander G Little et al.
BMC biology, 11, 26-26 (2013-03-28)
Thyroid hormone (TH) is best known for its role in development in animals, and for its control of metabolic heat production (thermogenesis) during cold acclimation in mammals. It is unknown whether the regulatory role of TH in thermogenesis is derived
Lihua Liu et al.
Environmental pollution (Barking, Essex : 1987), 219, 1122-1130 (2016-09-13)
Short-chain chlorinated paraffins (SCCPs) are ubiquitous in the environment and might cause adverse environmental and human health effects. Little is known about the relative toxicity of different SCCP compounds especially during development. The objective of this study was to characterize
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