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G0513

Sigma-Aldrich

Gly-Pro p-nitroanilide hydrochloride

≥99% (HPLC)

Synonym(s):

GP-pNA

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O4 · HCl
CAS Number:
103213-34-9
Molecular Weight:
328.75
MDL number:
MFCD00058170
UNSPSC Code:
12352204
PubChem Substance ID:
24895016
NACRES:
NA.32

Assay

≥99% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, faintly yellow to yellow

shipped in

wet ice

storage temp.

−20°C

SMILES string

Cl.NCC(=O)N1CCCC1C(=O)Nc2ccc(cc2)N(=O)=O

InChI

1S/C13H16N4O4.ClH/c14-8-12(18)16-7-1-2-11(16)13(19)15-9-3-5-10(6-4-9)17(20)21;/h3-6,11H,1-2,7-8,14H2,(H,15,19);1H

InChI key

VBBFIBMVFSUUBP-UHFFFAOYSA-N

Application

Gly-Pro p-nitroanilide hydrochloride has been used as a substrate in dipeptidyl peptidase-IV (DPP-IV) enzyme assay. It has also been used to determine DPP-IV inhibitory activity.

Substrates

Substrate for Dipeptidyl Peptidase IV.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Multifunctional biological activities of water extract of housefly larvae (Musca domestica)
Li H, et al
PharmaNutrition, 5(4), 119-126 (2017)
Chemical composition and inhibitory activities on dipeptidyl peptidase IV and pancreatic lipase of two underutilized species from the Brazilian Savannah: Oxalis cordata A. St.-Hil. and Xylopia aromatica (Lam.) Mart
Oliveira VB, et al.
Food Research International, 105, 989-995 (2018)
Monitoring of dipeptidyl peptidase-IV (DPP-IV) activity in patients with mucopolysaccharidoses types I and II on enzyme replacement therapy?Results of a pilot study
Hetmanczyk K, et al.
Clinical Biochemistry, 49(6), 458-462 (2016)
Antidiabetic evaluation of Hemionitis arifolia leaves by in vitro methods
Kumar KKR, et al.
Manipal journal of pharmaceutical sciences., 1(1), 13-20 (2015)
Yating Lu et al.
International journal of molecular sciences, 20(2) (2019-01-17)
Dipeptidyl peptidase IV (DPP-IV) inhibitors occupy a growing place in the drugs used for the management of type 2 diabetes. Recently, food components, including food-derived bioactive peptides, have been suggested as sources of DPP-IV inhibitors without side effects. Chinese black
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