E3031

Monoclonal Anti-dEGF Receptor, Cytoplasmic Domain antibody produced in mouse

~1.5 mg/mL, clone E-257, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Anti-Drosophila Epidermal Growth Factor Receptor, Anti-dEGFR
• MDL number: MFCD08705582
• UNSPSC Code: 51111800

Properties

• biological source: mouse
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: E-257, monoclonal
• form: buffered aqueous solution
• species reactivity: Drosophila
• concentration: ~1.5 mg/mL
• technique(s): immunohistochemistry: suitable; indirect ELISA: suitable; western blot: 0.25-0.5 μg/mL using recombinant cytoplasmic domain fragment of the Drosophila EGFR (amino acids 1200-1267)
• isotype: IgG1
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: Drosophila melanogaster ... Egfr(37455)

Description

General description

The signalling by dEGFR (also known as Torpedo or DER) is crucial for the development processes in Drosophila. The dEGFR signalling results in the activation of the canonical RAS/RAF/MEK/MAPK cascade. A variety of modulators such as Gro, TGF-α, Argos, Sprouty and Notch play an integrative role in EGFR signalling. The other pathways EGFR is involved in the development of the compound eye, larval, eye, wing and malphigian tubule development. Monoclonal Anti-dEGFR, Cytoplasmic Domain recognizes Drosophila Epidermal Growth Factor Receptor (EGFR). The antibody epitope resides within amino acids 1200-1267 of Drosophila EGFR.

Immunogen

recombinant cytoplasmic domain fragment of the Drosophila EGFR (amino acids 1200-1267).

Application

Anti-dEGF Receptor, Cytoplasmic Domain antibody may be used for immunoblotting at a working concentration of 0.25-0.5 μg/ml. The antibody is suitable for immunohistochemistry and ELISA.

Physical form

Solution in 0.01 M phosphate buffered saline containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.