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B1901

Sigma-Aldrich

Bradykinin Fragment 2-9

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C44H61N11O10
CAS Number:
16875-11-9
Molecular Weight:
904.02
MDL number:
MFCD00076264
UNSPSC Code:
12352200
PubChem Substance ID:
24891619
NACRES:
NA.32

Quality Level

200

Assay

≥97% (HPLC)

form

powder

UniProt accession no.

P01042

storage temp.

−20°C

SMILES string

NC(=N)NCCCC(NC(=O)C(Cc1ccccc1)NC(=O)C2CCCN2C(=O)C(CO)NC(=O)C(Cc3ccccc3)NC(=O)CNC(=O)C4CCCN4C(=O)C5CCCN5)C(O)=O

InChI

1S/C44H61N11O10/c45-44(46)48-20-8-16-30(43(64)65)51-38(59)32(24-28-13-5-2-6-14-28)52-40(61)35-18-10-22-55(35)42(63)33(26-56)53-37(58)31(23-27-11-3-1-4-12-27)50-36(57)25-49-39(60)34-17-9-21-54(34)41(62)29-15-7-19-47-29/h1-6,11-14,29-35,47,56H,7-10,15-26H2,(H,49,60)(H,50,57)(H,51,59)(H,52,61)(H,53,58)(H,64,65)(H4,45,46,48)

InChI key

ZZHVXIPXTCBVBE-UHFFFAOYSA-N

Gene Information

human ... KNG1 (includes EG:3827)

Amino Acid Sequence

Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

Biochem/physiol Actions

The des-arginine-1 bradykinin (BK) peptide (2-9) has no detectable contractile activity, inhibits ACE (angiotensin converting enzyme) and potentiates BK.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cristiano R Jesse et al.
Pharmacology, biochemistry, and behavior, 91(4), 573-580 (2008-10-22)
The objective of this study was to extend our previous findings by investigating in greater detail the mechanisms that might be involved in the antinociceptive action of p-methoxyl-diphenyl diselenide, (MeOPhSe)(2), in mice. The pretreatment with nitric oxide precursor, l-arginine (600
G S Bedi et al.
Biochimica et biophysica acta, 842(1), 90-99 (1985-09-27)
Four hybridoma cell lines have been established that secrete monoclonal antibodies to nonapeptide bradykinin. Bradykinin coupled to ovalbumin, using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide as coupling agent, was used to immunize BALB/c mice. Spleen cells from the immunized animals were fused to P3-X63-AG8-653 mouse
Julia Laskin et al.
Journal of the American Chemical Society, 125(6), 1625-1632 (2003-02-06)
Time- and collision energy-resolved surface-induced dissociation (SID) of des-Arg(1)- and des-Arg(9)-bradykinin on a fluorinated self-assembled monolayer (SAM) surface was studied by use of a novel Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) specially equipped to perform SID experiments.
B W Busser et al.
The Journal of urology, 160(6 Pt 1), 2267-2273 (1998-11-17)
Bradykinin 1 (B1) receptors have been shown to be upregulated at sites of inflammation. The purpose of this study was to determine the effect of lipopolysaccharide (LPS) on B1 receptor modulation in the isolated mouse bladder. The contractile responses of
S Mohammed et al.
Journal of mass spectrometry : JMS, 36(12), 1260-1268 (2001-12-26)
A novel tandem quadrupole mass spectrometer is described that enables gaseous collision-induced dissociation (CID) and surface-induced dissociation (SID) experiments. The instrument consists of a commercially available triple quadrupole mass spectrometer connected to an SID region and an additional, orthogonal quadrupole
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