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386A

Sigma-Aldrich

Leukocyte Acid Phosphatase (TRAP) Kit

Select reagents packaged in gelatin capsules

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About This Item

UNSPSC Code:
12352106
NACRES:
NA.47

shelf life

Expiry date on the label.

IVD

for in vitro diagnostic use

application(s)

hematology
histology

shipped in

wet ice

storage temp.

2-8°C

Principle

Peripheral blood or bone marrow preparations are fixed to a microscope slide. The resulting film is incubated in a solution of Naphthol AS-BI phosphoric acid and Fast Garnet GBC. Kit is used to demonstrate acid phosphatase and tartrate resistant acid phosphatase (TRAP) in blood, bone marrow and tissue touch preparations.

Kit Components Only

Product No.
Description
  • Acetate Solution (386-3) 50 mL
  • Acid Hematoxylin (285-2) 100 mL
  • Citrate Concentrate (386-1) 20 mL
  • Fast Garnet GBC Salt (kit only) 2 × 10
  • Naphthol AS-BI Phosphoric Acid (386-4) 40 mL
  • Tartrate Solution (kit only) 20 mL

related product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Annina Sipola et al.
BMC musculoskeletal disorders, 7, 56-56 (2006-07-15)
Endostatin is a C-terminal fragment of collagen XVIII which is a component of basement membranes with the structural properties of both collagens and proteoglycans. Endostatin has a major role in angiogenesis which is intimately associated with bone development and remodeling.
O A Adebanjo et al.
The Journal of cell biology, 142(5), 1347-1356 (1998-09-10)
We describe a physiologically significant mechanism through which interleukin-6 (IL-6) and a rising ambient Ca2+ interact to regulate osteoclastic bone resorption. VOXEL-based confocal microscopy of nonpermeabilized osteoclasts incubated with anti- IL-6 receptor antibodies revealed intense, strictly peripheral plasma membrane fluorescence.
Gui-Hua Quan et al.
International journal of molecular sciences, 16(12), 29496-29507 (2015-12-23)
Calycosin, an isoflavonoid phytoestrogen, isolated from Radix Astragali, was reported to possess anti-tumor, anti-inflammation, and osteogenic properties, but its impact on osteoclast differentiation remains unclear. In this study, we examined the effects of calycosin on osteoclastogenesis induced by RANKL. The
Yusuke Uto et al.
PloS one, 12(12), e0189893-e0189893 (2017-12-16)
Greater understanding and acceptance of the new concept "bone quality", which was proposed by the National Institutes of Health and is based on bone cells and collagen fibers, are required. The novel protein Semaphorin3A (Sema3A) is associated with osteoprotection by
Zhenheng Wang et al.
International journal of nanomedicine, 12, 5387-5397 (2017-08-11)
Wear particle-induced inflammatory osteolysis is the primary cause of aseptic loosening, which is the most common reason for total hip arthroplasty (THA) failure in the med- and long term. Recent studies have suggested an important role of gut microbiota (GM)
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