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Key Documents

ZZ-100MG-PUR

Sigma-Aldrich

Recombinant Mouse IgG B2

bottle of 100 mg

Synonym(s):

Antibody Blocker, HAMA, Passive Antibody Blocker, Purified Mouse IgG, Recombinant Mouse IgG

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

material

PETG bottle

clone

recombinant monoclonal

description

Phosphate Buffer Saline

Assay

≥90% (HPLC)

form

liquid

packaging

bottle of 100 mg

concentration

~5 mg/mL

technique(s)

ELISA: suitable
immunoblotting: suitable
lateral flow assay: suitable

pH

7.2

isotype

IgG

shipped in

dry ice

storage temp.

−20°C

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General description

Recombinant mouse IgG is a novel, sustainable replacement to serum-derived mouse IgG, providing manufacturers and researchers a tightly-controlled, non-animal-derived blocking solution to efficiently reduce nonspecific antibody interference in diagnostic assays while improving lot reproducibility and test accuracy, yet simplifying import regulations.
The recombinant mouse IgG is offered in two unique blends providing different formulations to select from and optimize for best performance results within a specific immunoassay. The formulas are designed to deliver equivalent or better blocking efficiency compared to serum-derived mouse IgG. This B2 recombinant mouse IgG was developed within a similar formulation as B1 but with directed blocking capability to specifically bind human anti-mouse antibodies present in serum/plasma samples and reduce non-specific binding in an immunoassay system using capture and detection antibodies.  In certain protocols, this directed binding may result in a lower concentration requirement as compared with standard serum-derived mouse IgG.

Features and Benefits

  • Sustainably sourced requiring no animal involvement.
  • Batch reproducibility with clonal-derived, cultured supernatant instead of pooled serum.
  • Security of scalable supply with on-time delivery.
  • Tightly controlled product manufacturing for optimal performance.
  • Simplified import regulations and restrictions.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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